Mostrando ítems 21-30 de 38
Martínez Delgado, Paula (Fecha de defensa: 2018-10-11)
Mitosis is a process that ensure the correct distribution of the chromosomes between the two newly generated cells, is tightly regulated by two main processes, protein degradation controlled by the APC ...
Bartrolí Comellas, Mariona (Fecha de defensa: 2018-11-16)
Targeting cancer metastasis has gained considerable importance in the recent years when aiming to increase patients’ overall survival. In Renal Cell Carcinoma (RCC), the discovery of metastatic biomarkers ...
Alvarez Villagomez, Carina Shianya (Fecha de defensa: 2017-09-19)
El epitelio gastrointestinal forma una barrera física y bioquímica que mantiene la segregación entre el huésped y la microbiota intestinal. La integridad de esta barrera es crítica en el mantenimiento ...
Rosell Cardona, Cristina (Fecha de defensa: 2022-07-08)
La malaltia d’Alzheimer (AD) és el tipus de demència més comú durant l’envelliment i una de les malalties neurodegeneratives més severes. L’AD es caracteritza per una pèrdua de memòria, la deposició de ...
Jiménez Félix, Alejandro (Fecha de defensa: 2021-01-11)
This thesis is centered on the study of PolyPurine Reverse Hoogsteen (PPRH) hairpins technology as a tool for both gene silencing and gene editing. PolyPurine Reverse Hoogsteen (PPRH) hairpins are ...
Bayod Giron, Carles (Fecha de defensa: 2021-05-07)
The nuclear receptors (NR) modulate gene transcription in a ligand-dependent manner throughout different mechanisms. A set of NR, including PPARγ and LXR, are important regulators of carbohydrate and ...
Cabezón Rodríguez, Itsaso (Fecha de defensa: 2017-04-03)
The blood-brain barrier is a well-coordinated and highly selective barrier whose main function is to regulate brain homeostasis and the transport of endogenous and exogenous compounds between the blood ...
Aubets Gil, Eva (Fecha de defensa: 2021-09-19)
This work is focused on the study of Polypurine Reverse Hoogsteen hairpins (PPRHs) as a gene silencing tool, and on the search of alternative methods for their delivery, including viral and non-viral ...
Torres Castro, Paulina (Fecha de defensa: 2019-12-16)
El sistema inmunitario no es totalmente funcional en el momento del nacimiento, sino que va desarrollando su capacidad defensiva frente a patógenos durante las primeras etapas de vida. Esta inmadurez ...
Morales Ferré, Carla (Fecha de defensa: 2022-04-29)
El sistema immunitari del nounat és immadur i, per tant, predisposa al nadó a patir infeccions, que en el cas dels nounats del gènere masculí semblen presentar una incidència i una gravetat majors que ...