Now showing items 41-51 of 51

    G1-Cdk modulation by time and stress 

    Pérez Paredes, Alexis E. (Date of defense: 2022-07-22)

    The cell cycle is regulated at different layers of control in either homeostatic or non-homeostatic conditions. Hence, in this work we analyse how time and stress modulate the cell cycle through the activity of the G1 ...

    CPT1c in specific hypothalamic nuclei and its role in lipid sensing and metabolic adaptation 

    Fosch Masllovet, Anna (Date of defense: 2022-07-28)

    Obesity has become a pandemic disease in the last 40 years. The WHO estimates that the population with overweight has nearly tripled since 1975, and the tendency is still growing. These data have an impact on health and ...

    Development of sol-gel silica-based 3D printable materials with tunable degradation, mechanical properties and drug release capacity for tissue engineering 

    Rodríguez González, Raquel (Date of defense: 2023-02-07)

    The bone is a very complex organ that participates in multiple critical functions for the human body. Bone can be affected by different health issues, such as physical trauma or tumor, and the body cannot regenerate large ...

    Development of novel bioinks formulations based on supramolecular self-assembled hydrogels for tissue regeneration. 

    Merino Gómez, María (Date of defense: 2023-04-21)

    The field of tissue engineering relies on the use of biomaterials as scaffolds for tissue and organ regeneration. If properly designed, these scaffolds can mimic the in vivo microenvironment while also providing initial ...

    Desarrollo de nuevos métodos para el análisis del polifosfato en células humanas 

    Sarrias Giménez, Ana (Date of defense: 2023-07-19)

    Nombre / Nom / Name Ana Apellidos / Cognoms / Surname Sarrias Giménez Dirección de correo electrónico / Adreça de correu electrònic / email address (opcional / optional) anasargim@gmail.com Departamento / Departament ...

    La cronicidad en enfermedad mental: políticas y modelos de atención integrados y centrados en las personas y la comunidad 

    Amo Mora, Isabel (Date of defense: 2023-09-09)

    La creciente prevalencia de enfermedades mentales y cronicidad orgánica genera una comorbilidad con impacto en la salud, calidad de vida y eficiencia de los modelos de atención. Se necesita un enfoque multidisciplinario ...

    Characterization of new mutations in transferrin, DMT1 and SEC23B causing rare iron metabolism-related diseases; and the discovery of RACGAP1 as the gene responsible for autosomal recessive congenital dyserythropoietic anaemia type III 

    Romero Cortadellas, Lídia (Date of defense: 2023-09-22)

    Iron is a biometal involved in many physiological processes that are essential for life. Iron metabolism is a complex and tightly regulated process both at the systemic and cellular level. Proper iron homeostasis relies ...

    Evaluation of biomarkers for studying new challenges in tobacco control 

    Pérez - Martín, Hipólito (Date of defense: 2023-11-17)

    El tabaquismo es reconocido a nivel global como un factor de riesgo significativo para la salud pública y una de las principales causas de muertes prevenibles. España ha implementado políticas de control del tabaco con el ...

    Development of C75-CoA loaded polymeric micelles targeting brain CPT1A: A novel nanomedicine-based approach to fight obesity and cancer 

    García-Chica, Jesús (Date of defense: 2023-12-01)

    Brain lipid metabolism has a key role in many physiological processes, and its malfunction is associated with a plethora of diseases, such as obesity and glioblastoma multiforme (GBM). Carnitine palmitoyl transferase 1A ...

    CPT1C-ABHD6 interaction in hypothalamic neurons: implications for bis (monoacylglycero) phosphate metabolism and the endolysosomal system 

    Reguera Moreno, Ana Cristina (Date of defense: 2023-12-04)

    El sistema endolisosomal juga un paper crític en la funció neuronal i ha emergit com a un potencial objectiu per al tractament de diverses malalties neuronals, com els trastorns neurodegeneratius i fins i tot l'obesitat. ...

    Nutrient-mediated regulation of AMPAR receptors’ trafficking through the malonyl-CoA – CPT1C axis 

    Rojas Martín, Rocío (Date of defense: 2023-12-22)

    Actualment hi ha un creixent interès en l'impacte de les dietes en la cognició. És àmpliament conegut que el cervell requereix una gran quantitat d'energia per dur a terme les seves funcions vitals. La gran majoria d'aquesta ...