Now showing items 9648-9667 of 11207
López Aladid, Rubén (Date of defense: 2022-10-20)
[spa] El pulmón siempre se ha considerado estéril. Sin embargo, el campo de la microbiota pulmonar se ha visto revolucionado por el avance de las técnicas moleculares. Cada individuo tiene un perfil de microbiota único, ...
Rosselló Xamena, Maria (Date of defense: 2021-12-10)
El manteniment de l’homeòstasi en organismes adults és cabdal per la continuïtat dels individus; desregulacions d’aquest equilibri porten a l’aparició de malalties. La planària és un model d’estudi en regeneració i remodelació ...
Serra Serra, Jordi (Date of defense: 2024-02-02)
[cat] La dialèctica sobre si l’objecte de la gestió documental ha d’incloure també la informació estructurada, o limitar-se només als documents, en tant que objectes discrets, es remunta a l’aparició de la tecnologia ...
Pavia Collado, Rubén (Date of defense: 2020-11-06)
[spa] Las sinucleínas son una familia de proteínas pequeñas y altamente conservadas en vertebrados, especialmente abundantes en las neuronas y típicamente enriquecidas en los terminales presinápticos, donde participan en ...
Tell Martí, Gemma (Date of defense: 2018-05-07)
El gen MC1R (codi OMIM: #155555) codifica pel receptor de la melanocortina 1 (MC1R) que s’expressa majoritàriament a la membrana dels melanòcits i està implicat en la regulació de la síntesi de melanina. El gen MC1R és ...
Soria Florido, María Trinidad (Date of defense: 2019-01-11)
Cardiovascular disease remains the first cause of death worldwide. Pharmacological trials and Mendelian randomization studies have failed to unequivocally prove an inverse association between HDL-C levels and the risk of ...
Casas Masnou, Eduard (Date of defense: 2019-11-25)
Gene regulation mechanisms control the level of transcription of each gene into RNA and the combination of expressed genes determines cell identity. Gene regulation is maintained by epigenetic mechanisms including DNA ...
O'Rourke, Thomas (Date of defense: 2021-04-27)
The human capacity for language is made up of various cognitive subcomponents, the convergence of which allows our species a unique ability to relay our thoughts. Identifying these subcomponents and establishing how they ...
Buñuel Moreno, Xavier (Date of defense: 2021-07-13)
The role of consumer-resource relationship is the basis of the structure and functioning of ecological communities. The traditional lens for studying such interactions have tended to omit the importance of the species ...
Rodríguez Muñoz, Laura (Date of defense: 2021-05-13)
The HMG-box protein Capicua (Cic) is a conserved transcriptional repressor with key functions downstream of receptor tyrosine kinase (RTK)-Ras-MAPK signaling pathways. In both Drosophila and mammals, Cic is expressed as ...
Mir Bonnín, Joan Francesc (Date of defense: 2016-07-11)
Previous studies have reported the importance of carnitine palmitoyltransferase (CPT) 1A as an essential part of downstream ghrelin signaling in the central nervous system (CNS) for the control of food intake. Lipid ...
Moreno Càceres, Joaquim (Date of defense: 2016-01-18)
The transforming growth factor-beta (TGF-β) is a cytokine involved in many physiological and pathological processes. Its dual role has been described in the liver, where it can either induce pro- or anti-apoptotic signals. ...
Aparicio García, María (Date of defense: 2020-12-09)
[eng] The arrival of antiangiogenic therapies represented a huge advance in the treatment of different tumors, such as renal carcinoma. However, despite initial good results, some tumors were able to develop different ...
Jesús Gil, Carmen de (Date of defense: 2021-06-01)
Psoriasis is a common immune-mediated inflammatory skin condition affecting around 2% of the population worldwide. Different disease subtypes have been described regarding their specific clinical phenotype: chronic plaques, ...
Safronova, Elena (Date of defense: 2016-11-04)
Many second language (L2) learners find L2 pronunciation difficult and experience perception and production problems leading to accented speech. There exists a great inter-learner variation in L2 phonological acquisition ...
Hereu Planellas, Mercè (Date of defense: 2019-07-19)
Modern lifestyles in an increasing number of human societies include consuming an excess of saturated fats and refined sugars as well as enjoying microbiologically aseptic environments. Maintaining the appropriate ...
Martinez Cristobal, Paula (Date of defense: 2016-12-01)
Protein homeostasis (proteostasis) results from the fine regulation of synthesis and degradation. The nuclear cofactor DOR/TP53INP2 was identified originally as a protein expressed in PML of nuclear bodies. However, in ...
Cuesta Borràs, Estefania (Date of defense: 2019-11-28)
Colorectal cancer (CRC) is a leading cause of death worldwide and tumour recurrence is a frequent complication that arises from minimal residual disease and shows up after a period of clinical dormancy. Slow-cycling cancer ...
Ribó Gené, Sílvia (Date of defense: 2017-12-01)
Childhood obesity and overweight can often cause severe complications, including hypertension, dyslipidemia, insulin resistance, type 2 diabetes, and non-alcoholic fatty liver disease, amongst other disorders. Several ...
Pérez Martí, Albert (Date of defense: 2017-03-13)
Obesity and associated metabolic diseases have reached epidemic proportions, affecting not only high-income countries but also low- and middle-income ones. In this context, the search for therapeutic approaches to treat ...