Ara mostrant els elements 2841-2860 de 3292
Moncagatta, Paolo (Data de defensa: 2015-06-02)
Citizen support for democratic rule is considered by many scholars as a necessary condition for the consolidation and stability of democratic systems. This dissertation studies support for democracy from three different ...
Coll Camenforte, Sergi (Data de defensa: 2019-12-10)
Due to health risks associated to the use of glucocorticoids (GC) and their potential ergogenic effects, systemic GCs are prohibited in sports competitions. However, local GC administrations are allowed for therapeutic ...
Martínez Torres, Sara (Data de defensa: 2019-12-12)
The endocannabinoid system (ECS) is an endogenous neuromodulatory system widely expressed in the central nervous system and peripheral organs, where it fine-tunes numerous physiological functions. The ECS is under study ...
Laguna Tuset, Ariadna (Data de defensa: 2008-12-18)
El gen DYRK1A es troba situat en una regió del cromosoma 21 humà que s'ha associat a alteracions en el neurodesenvolupament. Aquest treball mostra com canvis en la dosis gènica de Dyrk1A en el ratolí causen una alteració ...
García Blanco, Alejandra (Data de defensa: 2023-07-06)
The easy access to hypercaloric and palatable foods is a major contributing factor for compulsive eating and food addiction development. The prevalence of food addiction measured with the validated Yale Food Addiction ...
Saus Martínez, Ester (Data de defensa: 2010-11-24)
In this thesis we have studied genetic elements potentially contributing to the pathophysiology of psychiatric disorders, focusing on different sources of human genome variability, including SNPs and CNVs, which can affect ...
Haber, Marc (Data de defensa: 2013-12-05)
Patterns of human genetic diversity suggest that all modern humans originated from a small population in Africa that expanded rapidly 50,000 years ago to occupy the whole world. While moving into new environments, genetic ...
Pogorelova, Iryna (Data de defensa: 2016-12-19)
The present dissertation investigates the impact of university study abroad (SA) programmes on intercultural adaptation and intercultural sensitivity of bilingual students from a multilingual and multicultural background. ...
Herrera Nieto, Pablo (Data de defensa: 2020-07-17)
Over the last decades molecular dynamics simulations have been successfully applied to relevant biological problems such as protein-ligand, protein-protein binding as well as protein folding. A perfect challenge for molecular ...
Ortiz Romero, Paula (Data de defensa: 2019-11-18)
Williams-Beuren syndrome (WBS) is a rare neurodevelopmental disorder caused by a heterozygous deletion of ~1.5 Mb in chromosome region 7q11.23. The use of murine models of the disease has helped to broaden the knowledge ...
Gallego Román, Ana María (Data de defensa: 2022-05-26)
Binge-eating disorder (BED) is a chronic eating disturbance that affects 1.6-2.0% of people worldwide. It is characterised by recurrent episodes of consuming large amounts of food in a short period, together with a sense ...
Barreiro Portela, Esther (Data de defensa: 2002-06-18)
Protein nitration is considered as a marker of reactive nitrogen species formation. Heme oxygenases (HOs) are important for the defence against oxidative stress. We evaluated the involvement of the neuronal (nNOS), the ...
García López, Roberto (Data de defensa: 2018-04-06)
Genome-wide association studies have been very useful tools in the last years to relate genes and diseases. Thereby, single nucleotide polymorphisms have been linked to increased ORMDL3 expression and to different pathologies ...
Touriño Raposo, Clara (Data de defensa: 2009-02-17)
La 3,4-metilendioximetamfetamina (MDMA, èxtasi) i el cannabis són dues drogues les quals es consumeixen conjuntament de manera habitual. Malgrat que tots dos compostos presenten propietats reforçant i potencial addictiu, ...
Sánchez Osuna, María (Data de defensa: 2014-12-19)
Glioblastoma multiforme, one of the most aggressive and lethal tumors, is characterized by a high apoptosis resistance. This doctoral thesis addresses the biochemical behavior of diverse glioblastoma cells, including primary ...
Moscoso Castro, Maria (Data de defensa: 2016-11-28)
The adenosinergic system is a neuromodulatory complex acting on four receptor subtypes with varying distributions throughout the central nervous system. This system contributes to homeostasis and regulates several physiological ...
Calzolari, Simone (Data de defensa: 2013-11-15)
Durant el desenvolupament embrionari, els teixits s’especifiquen gradualment fins a que adquireixen un destí final. En els vertebrats el Sistema Nerviós Central (SNC) deriva del tub neural, una estructura embrionària ...
Gutiérrez Martos, Miriam (Data de defensa: 2018-06-08)
Drug addiction and several eating disorders share striking similarities in their behavioural patterns triggered by the presence of neuronal alterations in the brain reward circuit. In this Thesis, we investigate the ...
Ill-Raga, Gerard (Data de defensa: 2010-09-28)
Nitric oxide (NO) is a neurotransmitter involved in memory processes. Currently, the only recognized physiological signalling pathway controlled by NO is the activation of guanylyl cyclase. In this thesis, we propose an ...
Guix Ràfols, Francesc Xavier (Data de defensa: 2009-01-22)
Aquesta tesi demostra que el peroxinitrit produït com a conseqüència del pèptid beta-amiloide (A) contribueix l'augment de la relació A42/A40 que ocorre a la malaltia d'Alzheimer. L'A42 ...