Universitat Pompeu Fabra
Now showing items 21-40 of 1151
El "Questionnaire for Assessing the Childbirth Experience (QACE)" busca identificar mujeres con una experiencia negativa del parto y evitar que tenga repercusiones en siguientes embarazos o en su relación de pareja. El ...
Although universal and unavoidable, aging does not occur in a uniform way. In this dissertation, we assessed the effects of early life exposure to pro-inflammatory risk factors (air pollution and obesity) on mitochondrial ...
Cytomegalovirus (CMV) infection in kidney transplant recipients (KTR) is frequent and may reduce graft and patient survival. T lymphocytes are essential to control the virus, which promotes the adaptive differentiation of ...
microRNAs are small non-coding RNAs with crucial roles in gene regulation and whose contribution to animal evolution has been largely demonstrated. In this thesis we explored some functional consequences of microRNA sequence ...
Peptide-based vaccines have raised as an attractive alternative strategy to overcome many of the limitations of conventional vaccines. Some drawbacks for an optimal immune response in vivo are, a poor immunogenicity, ...
Des de fa anys l'atenció al part està perseguint la fita d'aconseguir donar una assistència més humana i fisiològica a tot el procés, s'han creat guies de pràctica clínica, grups de treball, estratègies nacionals, etc., ...
Almost 20 years of Neandertal paleogenetics studies have significantly increased our knowledge about their evolutionary history. The analysis of DNA recovered from Neandertal remains to date, suggest that although they ...
La alta variabilidad interindividual en las manifestaciones de dolor neuropático puede conducir a una respuesta diferencial de los pacientes a los tratamientos, y sugiere la idoneidad de terapias más personalizadas en lugar ...
Air pollution is a major public health concern, leading to worldwide morbidity and premature mortality. In the recent years, exposure to air pollution has also been linked to neurological and neuropsychological diseases, ...
Hazardous drinking in the elderly has become an important public health problem due to the ageing of the population and the fact that alcohol-related consequences are magnified in this age group. However, to date, few ...
A multiple sequence alignment (MSA) provides a description of the relationship between biological sequences where columns represent a shared ancestry through an implied set of evolutionary events. The majority of research ...
Gene regulation orchestrates the development of different cell types and organs from the same genetic blueprint. While the basic mode of gene regulation is driven by transcription factors, there are a variety of other ...
Alternative splicing (AS) is a mechanism of post-transcriptional regulation that plays an important role during development and in the maintenance of stem cell pluripotency. The dynamics of AS regulation during somatic ...
Recent epidemiological evidence on effect of air pollution and pregnancy outcomes is inconsistent. Differences in study design, sample size, population characteristics, control for confounders, air pollution measurements ...
Until relatively recently, many groups of terrestrial reptiles were considered to contain only few species vastly distributed across the Arabian Peninsula. This was mostly the result of the apparent morphological uniformity ...
Cancer is a complex disease caused by somatic alterations of the genome and epigenome in tumor cells. Increased investments and cheaper access to various technologies have built momentum for the generation of cancer genomics ...
In the last decade recurrent neural networks have revolutionized the field of artificial intelligence. Their cyclic connections provide them with memory and thus with the capability of modeling processes with temporal ...
The main objective of this thesis is to improve understanding of citizen participation in science in Spain. Specifically, it analyses the characteristics of current participatory practices and the opinions and attitudes ...
The aim of this thesis is to apply Identity by Descent (IBD) methodology to identify ancestry connections among individuals from genetically similar populations. Recombination events diminish the likelihood to detect IBDs. ...
New approaches are needed to manage and analyze the enormous quantity of biological data generated by modern technologies. Existing solutions are often fragmented and uncoordinated and, thus, they require considerable ...
