Universitat Pompeu Fabra
Now showing items 2201-2220 of 3222
To address one of the most fascinating questions in the history of life, the origin of animal multicellularity, we needed experimentally tractable representatives from each of the unicellular lineages, that are relative ...
At the end of G1 phase, cells have to decide between continue proliferation or remain in a quiescent state (G0). This decision point, known as “Start” in yeast and “Restriction Point” in metazoans, marks irreversibly the ...
Snail1 is the master regulator of the Epithelial-to-Mesenchymal Transition (EMT) and is also crucial for fibroblast activation upon TGFβ signaling. In cancer, Snail1 expression in primary tumors correlates with the appearance ...
El paradigma clàssic on un medicament interacciona amb un únic target biològic vinculat a una malaltia es posa en dubte. Actualment es reconeix que un medicament interacciona amb múltiples targets biològics i que aquests ...
The next Wi-Fi generation poses in front of a massive challenge as the main enabler for new services and applications. Traffic requirements are expected to keep rising year over year, challenging Wi-Fi networks to cope ...
What is the nexus between EU external migration policies and the democratization of Southern Mediterranean countries (SMCs)? Although being two essential components of EU external action and central elements within ...
In this PhD I have used NGS technologies in different organisms and scenarios such as in ENCODE, comparing the conservation and evolution of long non-coding RNA sequences between human and mouse, using experimental evidences ...
The CHRNA5/A3/B4 genomic cluster encodes for the alpha5, alpha3 and beta4 subunits of the nicotinic acetylcholine receptors (nAChRs). Human genetic studies have revealed a significant association of variants in this ...
Esta investigación busca comprender el lenguaje poético creacionista del poeta Vicente Huidobro desde una constante escatológica, que se articula en su poesía a partir de ciertas ideas estéticas y éticas románticas, s ...
En esta tesis se interpreta a través del prisma conceptual del nihilismo el desarrollo de la literatura española de entreguerras, y el papel central de los escritores en el reconocimiento de desorientación del hombre ...
Ingested nitrate is a precursor of N-nitroso compounds that are carcinogens in animals, with limited evidence in humans. The main objective of this thesis was to evaluate whether the exposure to nitrate through drinking ...
La evidencia sobre el efecto de las nitrosaminas (NA) sobre el cáncer gástrico (CG) es insuficiente. El objetivo fue evaluar el efecto de las NA (exógenas y endógenas ) y sus alimentos fuente sobre el riesgo de CG. El ...
Several studies support the contribution of antibody-dependent NK cell cytotoxicity (ADCC) to the clinical efficacy of anti-HER2 therapeutic antibodies in HER2-positive breast cancer. Novel anti-HER2 antibody drug conjugates ...
Epidemiological evidence is limited regarding the effects of long-term exposure to traffic-related air pollution and to traffic noise on blood pressure (BP). This thesis aims at (a) assessing the long-term co-exposure ...
In this thesis, a set of some prevailing rate-based models for bistable perception have been considered in order to find the implications of the novel results reported in Pastukhov & Braun (2011). These authors have ...
This dissertation contains three studies, which explore various questions about verbal aspect and how it is affected by the process of nominalization. The first study examines the type of regular eventive nominalizations ...
El binarismo de identidad limita la expresión de la identidad a dos identidades opuestas. Es una construcción social y se refuerza a través de los medios de comunicación. Los zines, o folletos auto-editados, ofrecen una ...
During mitotic spindle assembly, γ-tubulin ring complexes (γTuRCs) nucleate microtubules at the centrosome, around mitotic chromatin and, by augmindependent recruitment, from pre-existing microtubules. The analysis of ...
Most physical ablation modalities for cancer treatment are focal and are based on thermal damage. Despite their regular clinical use as an alternative to surgical resection, their thermal principle of operation entails ...
Co-speech gestures are children’s first path towards communication. Further in development, research has primarily focused on the role of iconic gestures in boosting children’s narrative abilities, while less is known ...
