Herrera Nieto, Pablo (Date of defense: 2020-07-17)
Over the last decades molecular dynamics simulations have been successfully applied to relevant biological problems such as protein-ligand, protein-protein binding as well as protein folding. A perfect ...
Núñez Ollé, Marc (Date of defense: 2014-07-04)
Cyclin O, a novel identified CDK1 and CDK2-binding cyclin, has been demonstrated to be required for γ-radiation induced apoptosis in a lymphoid cell line. Ɣ-radiation induces the formation of DSBs in ...
Stanley, Nathaniel H. (Date of defense: 2015-04-24)
This thesis has been about the use of a simulation technique, known as molecular dynamics simulations, to study biophysics in proteins that have historically been difficult to study with other methods. ...
Domènech Guil, Alba (Date of defense: 2018-03-02)
Schizosaccharomyces pombe, com tots els organismes aeròbics, requereix l’oxigen per viure i té que lidiar amb la conseqüent toxicitat associada dels productes derivats de l’oxigen. Per mantenir l’ambient ...
Xiao, Can (Date of defense: 2021-10-07)
The existence and progression of certain diseases are associated with the imbalances of different biomolecules. The multiplex sensing of hydrogen peroxide and pH can be potentially used for understanding ...
Latorre Doménech, Pablo (Date of defense: 2021-06-15)
Virtually all living organisms are challenged by changes in their environment, such as sudden increases in osmolarity. To cope with these stresses, cells have developed stress responses that tune every ...
Val Casals, Maria (Date of defense: 2020-07-09)
Els ritmes circadians són oscil·lacions diàries en paràmetres fisiològics necessaris per a què els organismes adaptin la seva activitat als cicles de llum i foscor. A nivell molecular, la maquinària ...
Cirillo, Davide (Date of defense: 2016-05-09)
The purpose of my doctoral studies has been the development of bioinformatics methods to quantitatively evaluate associations between proteins and nucleic acids (NAs). This thesis aims at providing ...
Meyer, Markus (Date of defense: 2010-03-26)
The informational content of 3' splice sites is low and the mechanisms whereby they are selected are not clear. Here we enunciate a set of rules that govern their selection. For many introns, secondary ...
Rodríguez-Morató, Jose (Date of defense: 2016-06-20)
Hydroxytyrosol [2-(3,4-dihydroxyphenyl)ethanol], a potent bioactive molecule mainly present in virgin olive oil and to a lower extent in wine, is also a by-product of dopamine metabolism. In a previous ...