Ara mostrant els elements 1-10 de 12
Puig Tintó, Marta (Data de defensa: 2023-05-02)
The exocyst is an heterooctameric protein complex that tethers secretory vesicles to the plasma membrane during exocytosis. Each exocytic event is mediated by 10-15 exocysts. However, how multiple ...
Balbastre Català, Borja (Data de defensa: 2022-10-27)
Dual-specificity tyrosine-regulated kinases (DYRKs) are a conserved family of protein kinases present in all eukaryotes. In mammals, the association of DYRKs with a wide variety of putative substrates ...
Baltzis, Athanasios (Data de defensa: 2023-03-20)
Recent advances in deep learning techniques have revolutionised protein structure modelling. Since AlphaFold2’s release, a set of tools have now become available to predict native-like structures at ...
Barrero Asencio, Mercedes (Data de defensa: 2023-03-02)
During reprogramming of somatic cells into induced pluripotent stem cells (iPSCs), the epigenome needs to be reset. A prime example of this is the reversal of the silent state of the inactive X chromosome ...
Mansouri, Leila (Data de defensa: 2023-03-27)
El continuo aumento de los proyectos de producción de datos genómicos a gran escala, como el "Earth BioGenome Project" (Lewin et al., 2018), pone los métodos de análisis de datos bajo una presión sin ...
Cianferoni, Damiano (Data de defensa: 2023-10-09)
Aquesta tesi presenta diversos avenços que inclouen: (i) noves funcionalitats afegides a la “suite” d'eines de disseny de proteïnes FoldX per permetre als usuaris treballar amb qualsevol tipus de molècula; ...
Val Casals, Maria (Data de defensa: 2020-07-09)
Els ritmes circadians són oscil·lacions diàries en paràmetres fisiològics necessaris per a què els organismes adaptin la seva activitat als cicles de llum i foscor. A nivell molecular, la maquinària ...
Ivancic, Dimitrie (Data de defensa: 2024-04-03)
Methods for genome engineering have enabled construction of synthetic genomes, therapeutically reprogrammed cells, synthetic organs, and modification of human genomes. Design and discovery of genome ...
Morales Pastor, Adrián (Data de defensa: 2024-04-11)
G protein-coupled receptors (GPCRs) are central to cellular signaling and pivotal in drug development. This thesis investigates allosteric communication in GPCRs, crucial for their effective modulation ...
Cabús, Lluc (Data de defensa: 2024-03-15)
RNA is a molecule that is released by the different tissues into the circulation. When it is found in the circulation it is called cell-free RNA (cfRNA). This type of molecule has great potential as ...