Universitat de Girona
Now showing items 94-113 of 119
Brugada syndrome (BrS) is a cardiac electrical disease with high susceptibility to sudden cardiac death. Approximately 25-30% of BrS patients are explained by pathogenic variants in coding sequences of cardiac ion channels, ...
Sudden cardiac death (SCD) is defined as a natural and unexpected death due to cardiac etiology. In addition, when the cause of death remains unexplained after a complete autopsy, a cardiac arrhythmia is suspected as a ...
Childhood obesity is one of the most important public health problems and is associated with cardiometabolic risk factors (CMR). Low-grade inflammation plays a prominent role in the development of cardiometabolic alterations ...
Risk of cerebral hypoperfusion during carotid endarterectomy arterial is the main limiting factor of this technique. Shunt allows partial maintenance of cerebral perfusion during clamping. We analyze the hemodynamic ...
Non-alcoholic fatty liver disease (NAFLD) has become the leading cause of chronic liver disease worldwide, involving a spectrum of disturbances mainly characterized by fatty acid infiltration and fat deposition in the liver ...
Multiple sclerosis (MS) is considered a chronic inflammatory and neurodegenerative disease, characterized by the existence of demyelinated areas in the central nervous system, infiltration of inflammatory cells in the ...
ENG- The traumatic injury of the spinal cord causes the onset of pain in 65% of patients. Almost 50% of them do not respond to current analgesic treatments. It is a serious health condition with considerable impact on ...
We studied the relationship between the circulating levels of the innate immune system molecules (α-defensins and BPI) and the acquired immune system (IgG, IgA and IgM) with obesity and cardiometabolic risk factors in ...
Pain in the buttock region without lumbar pathology will lead us to focus the study on the region of the subgluteal space. This is defined as the deep gluteal syndrome. The deep gluteal syndrome is a condition with a very ...
The objective of this thesis is to explore in greater depth the process of creating a public health observatory and the processing of the information needed to take territorial decisions in the county of Alt Empordà. The ...
The endothelium, the lining of our blood vessels, plays a crucial role in controlling functions such as blood flow, clotting and inflammation. When it does not function properly, called endothelial dysfunction, it can lead ...
Huntington’s disease (HD) is a neurodegenerative genetic disorder with no effective treatment characterized by motor discoordination, deficits in cognitive function (acquiring new knowledges, memory, understanding…), and ...
ENG- HER2 positive breast cancer represents approximately 15-20% of breast cancer and it is associated with higher grade, more aggressive phenotype and worse prognosis. The prognosis of these patients has dramatically ...
Non-small cell lung cancer (NSCLC) is a challenging disease to treat. Despite several decades of improved clinical progress, there is an unmet need to investigate how therapeutic resistance develops. In particular, managing ...
ENG- Imprinted genes are expressed only from one parental allele, either from the mother or the father. They play fundamental roles in fetal and placental growth, as well as in neurobehavioral traits. These genes are ...
Hydrogen sulfide (H2S), regarded as the third gasotransmitter, plays diverse physiological and pathological roles in the body along with another two gasotransmitters, including nitric oxide (NO) and carbon monoxide (CO). ...
Huntington's disease (MH) is a progressive neurodegenerative disorder characterized by a motor dysfunction, cognitive impairment, and psychiatric symptoms. At neuropathological level, it has been described that cognitive ...
The sodium channel β2 subunit is a component of the voltage-gated sodium channel (NaV), a large multimeric protein complex. In the heart, NaV is mainly composed of a pore-forming α subunit, NaV1.5, and two associated ...
ENG- Fibromyalgia syndrome is a chronic disease that presents chronic diffuse musculoskeletal pain combined with fatigue, sleep alterations and cognitive alterations. Currently, about 2.3% of the world's population suffers ...
ENG- Obesity is a complex chronic disease linked to adipocyte dysfunction and a low-grade inflammatory condition leading to the impaired synthetic and secretory activity of hyperplastic depots of adipose tissue. As a ...
