Universitat de Barcelona
Now showing items 46-65 of 229
[eng] Advances in capturing technologies have yielded a massive production of large-scale molecular data that describe different aspects of cellular functioning. These data are often modeled as networks, in which nodes are ...
Understanding how organisms adapt to their environment remains an open question in Biology. So far, most projects focus on the study of single nucleotide polymorphism variants, while other types of mutations, likely to ...
Esta tesis se basa en diagnóstico de pacientes con deficiencia de 2 metil 3 hidroxibutiril CoA deshidrogenasa (MHBD o HSD10) y en el estudio de la fisiopatología de esta enfermedad y de su implicación en la Enfermedad de ...
Population ecology is a scientific discipline primarily interested in the ecological processes that make the number of individuals in a population to change over space and time, and by focusing on populations as fundamental ...
Widespread species have traditionally received much less attention than rare and endemic ones. However, they are crucial in macroecological patterns and in ecosystem structure and functioning. Thus, understanding the ...
Shallow-water rocky ecosystems in temperate areas are dominated by macroalgae, whilst zooxanthellate corals are extremely rare. In an era of global change, sea warming plays a crucial role in the widespread phase shifts ...
Sexual division of labour involving the use of teeth in non-masticatory activities in the Tigara population form Point Hope did not affect the wear of the upper and lower first molars and, therefore, food chewing was the ...
[spa] Establecer la naturaleza patogénica de las variantes de secuencia en ATM, un gen asociado con el cáncer de mama y otros cánceres hereditarios, es crucial para brindar una atención adecuada a los pacientes. Sin embargo, ...
La función principal del sistema de reparación de apareamientos erróneos (MisMatch Repair, MMR) es corregir los errores principalmente introducidos por las DNA polimerasas durante la replicación del genoma. Las mutaciones ...
INTRODUCCIÓN: En el laboratorio clínico, antes de entregar el informe al solicitante, se realiza una revisión final de los resultados con la finalidad de detectar la existencia de resultados sospechosos de contener errores ...
The identification and analysis of genomic variation across individuals has been central in biology, first through comparative genomics to answer evolutionary questions, and then in the context of biomedicine, where it is ...
Somatic mutations are those that arise after the zygote is formed and are therefore inherited by a fraction of the cells of an individual. Their relevance in certain skin diseases has been known for almost half a decade ...
The incremental application of supercomputers to offer solutions to complex problems has motivated the usage of computational modeling tools in drug design pipelines. Specifically, small low-affinity compounds are modified ...
[eng] Epigenetic mechanisms play a vital role in gene expression regulation and phenotype determination. This thesis aimed to comprehensively investigate the transcriptome, the methylome and the influence of intrinsic (such ...
Lakes are ecosystems exposed to the combined influence of climate and catchment processes. Lakes collect and archive evidence of these forcings in their sediments through of a complex interaction with internal processes. ...
The aim of this thesis was to explore the distribution of the taxonomic, phylogenetic and functional components of plant diversity in high mountains, and to show how different components of diversity have responded to ...
Submarine canyons are major topographic structures forming deep incisions in shelfs and continental margins around the globe. Due to their topographic characteristics, canyons influence both local hydrodynamic conditions ...
Bivalves living in large aggregations of individuals (reefs or beds), such as mussels, clams, cockles and some high trophic predators such as sea stars, play an essential ecological role in the structure, integrity, ...
The overarching aim of my thesis was to assess the role of environmental variability and specially of perturbations in the population dynamics of social vertebrates. Our results emphasize the need to collect individual, ...
1. El paper que tenen les ceramidases en diferents malalties humanes va guanyant interès. Tot i així, la recerca en aquest àmbit ha estat obstaculitzada per la manca d’inhibidors i substrats específics per les diferents ...
