Universitat de Barcelona
Ara mostrant els elements 1-20 de 26
[eng] The field of cancer treatment has shifted towards personalized medicine, driven by advancements in understanding molecular and genetic abnormalities and identifying specific targets within cancer cells. Precision ...
Network and systems biology disciplines could revolutionize the study of complex diseases by taking proteins back to their context, considering a much broader perspective of their environment without losing the molecular ...
Los neuroblastomas (NB), ganglioneuroblastomas (GNB) y ganglioneuromas (GN) conforman el grupo de los tumores neuroblásticos (TN). Se trata de un grupo muy heterogéneo de tumores del desarrollo que pueden involucionar ...
Esta tesis consiste en el estudio de la regulación por microRNAs del proceso de metástasis de carcinomas ductales invasivos de mama. Hemos encontrado una expresión alterada de varios microRNAs en muestras tumorales, ...
Las personas con insuficiencia renal crónica (ERC) suelen manifestar sentirse más fatigados al terminar la sesión de diálisis (HD). Cabe destacar que se trata de una población compuesta por pacientes que pueden presentar ...
INTRODUCCIÓ: Actualment el bypass gàstric en Y-de-Roux és la tècnica més freqüent portada a terme en l’àmbit internacional en què, en ser de tipus mixta, es produeix una combinació dels elements restrictius i de malabsorció. ...
El cáncer de pulmón de célula pequeña (CPCP) es el subtipo mas agresivo del cáncer de pulmón. Mas de la mitad de los pacientes se diagnostican con enfermedad diseminada, donde el tratamiento de elección desde la década de ...
[eng] Colorectal cancer (CRC), particularly its metastatic forms, poses significant therapeutic challenges, with immune checkpoint blockade (ICB) therapies providing limited benefits to patients whose metastasis lack T cell ...
[eng] The clinical management of hereditary breast and ovarian cancer (HBOC) families relies on identifying germline pathogenic variants in cancer susceptibility genes, such as BRCA1 and BRCA2. However, genetic testing ...
[eng] Malignant Peripheral Nerve Sheath Tumors (MPNSTs) are aggressive soft-tissue sarcomas. They usually appear in the clinical context of Neurofibromatosis type 1 (NF1), however, they also occur at a low frequency in the ...
SNAIL1 is a transcription factor with roles in repression of epithelial genes and enhancement of mesenchymal genes. As such, it plays a key role in Epithelial-to-mesenchymal transition and in fibroblast activation into ...
Metastatic breast cancer (BCa) is the leading cause of death in BCa patients. Current therapies for BCa aim at cell proliferation and, therefore, latent disseminated cells are able to escape treatment. For this reason, ...
La malaltia de Gaucher (GD) forma part d'un conjunt de malalties que es coneixen amb el nom de "malalties d'acumulació lisosómica". La GD n'és la més prevalent i en la majoria de casos és causada per mutacions en el gen ...
Colorectal cancer (CRC) is a major health burden with large numbers of new cases worldwide and high disease-specific mortality, despite great advances made towards improving patient clinical outcomes. It arises through the ...
[eng] During radiotherapy (RT) some healthy tissues are irradiated inevitably causing side effects, without being able to predict nowadays which patients will develop this toxicity. To date, the biomarker with the best ...
El análisis de la expresión global y de número de copias de DNA en tumores primarios y líneas celulares de cáncer de pulmón reveló la presencia de amplificación génica en los cromosomas 11q12, 13q34 y 6p22. En los cromosomas ...
Breast Cancer (BC) is one of the major causes of cancer deaths in women. BC is a heterogeneous disease, and within the heterogeneity of the tumor, Tumor-Initiating Cells (TICs) have been reported as important drivers in ...
[spa] La lesión por isquemia-reperfusión (IR) es la mayor causa de pérdida y disfunción de tejidos y órganos en trasplantes clínicos, como es el trasplante hepático. Durante la isquemia, la carencia de oxígeno provoca ...
Colorectal cancer (CRC) kills around 700,000 people worldwide every year. The majority of these deaths are the result of dissemination of the disease to foreign organs. Despite undergoing curative resection of the primary ...
[eng] Cancer is the leading cause of death worldwide, with lung and liver cancers being major contributors. Liver cancer is often preceded by cirrhosis, considered as the final stage of chronic liver disease. Recognizing ...
