Mostrando ítems 141-149 de 149
Ivancic, Dimitrie (Fecha de defensa: 2024-04-03)
Methods for genome engineering have enabled construction of synthetic genomes, therapeutically reprogrammed cells, synthetic organs, and modification of human genomes. Design and discovery of genome ...
Morales Pastor, Adrián (Fecha de defensa: 2024-04-11)
G protein-coupled receptors (GPCRs) are central to cellular signaling and pivotal in drug development. This thesis investigates allosteric communication in GPCRs, crucial for their effective modulation ...
Vandelli, Andrea (Fecha de defensa: 2023-04-19)
Ribonucleoprotein condensates such as stress granules (SGs) and processing bodies (PBs) form in response to specific stimuli in the cell. Even though the key protein and RNA elements of these condensates ...
Cabús, Lluc (Fecha de defensa: 2024-03-15)
RNA is a molecule that is released by the different tissues into the circulation. When it is found in the circulation it is called cell-free RNA (cfRNA). This type of molecule has great potential as ...
Kennedy, Keith Endres (Fecha de defensa: 2023-05-30)
This thesis focuses on the multiscale nature of the biological process that underpin the function of all living systems. A first project centers on the disease known as multiple sclerosis, and utilizes ...
Galera Laporta, Letícia (Fecha de defensa: 2019-02-08)
Bacterial proliferation has been studied for more than 100 years, but our knowledge of the mechanisms that control its dynamical aspects is still very limited. In this Thesis we have studied, at both ...
Bae, Hansol (Fecha de defensa: 2024-04-26)
Epigenetic modification serves as a crucial mechanism in regulating gene expression and facilitating cellular adaptation to environmental stress. This study aimed to identify histone residues and their ...
Bota, Patricia Mirela (Fecha de defensa: 2024-05-21)
Protein-protein interactions (PPIs) are fundamental in driving biological processes and maintaining life’s diverse functions. They play a key role in cellular regulation, facilitating our understanding ...
Pallarès-Masmitjà, Maria (Fecha de defensa: 2022-12-19)
The need for efficient targeted integration of large DNA fragments in mammalian genomes is indisputable, although several nuclease-based technologies have been lately developed for small allele genome ...