Relevant Molecular and Functional G.Protein Coupled Receptor Interactions in Neuroinflammation and Addiction = Interaccions moleculars i funcionals de receptors acoblats a proteïna G rellevants en neuroinflamació i addició 

    Angelats Canals, Edgar (Fecha de defensa: 2018-09-14)

    G-protein coupled receptors (GPCR) constitute a complex and versatile superfamily of membrane receptors with relevance in maintaining homeostasis. The thesis project has focused in members of this superfamily: the CB1 and ...

    The role of the G-protein coupled receptor 120 (GPR120) on the FGF21 system in white and brown adipose tissues 

    Quesada López, Tania Paloma (Fecha de defensa: 2018-07-09)

    Obesity prevalence has tripled in the last fifty years. For this reason, it is considered the pandemic of the century. It is characterized by the accumulation of metabolic abnormalities triggered by an increase in the size ...

    Study of the metabolic reprogramming associated to metastasis in colon cancer 

    Tarragó Celada, Josep (Fecha de defensa: 2020-09-16)

    Metastasis is the main cause of cancer-related deaths and it is of great biomedical importance to develop new therapeutic strategies that specifically target metastatic cells. Therefore, a better comprehension of the process ...

    Targeting metabolic reprogramming in metastatic colorectal and prostate cancer cells to prevent therapeutic failure 

    Hernández Carro, Claudia (Fecha de defensa: 2024-03-19)

    [eng] Prostate and colorectal cancer are among the cancer types with the highest recurrence and mortality rates. The emergence of drug resistance poses a considerable challenge for effective treatment, especially in the ...

    Turnover of voltage-gated potassium channel Kv 1.3 

    Styrczewska, Katarzyna (Fecha de defensa: 2017-09-22)

    Voltage-gated K channels (Kv) is large family of channels that are expressed in both excitable and non-excitable cells. In excitable cells they contribute to the control of resting membrane potential and action potentials ...

    Using pacient-specific IPSC derived dopaminergic to investigate Parkinson's disease: a new prospective in stem cell research and application = Utilització de neurones dopaminèrgiques específiques de pacients derivades de cèl·lules pluripotents induïdes (IPSC) en la investigació de la malaltia de Parkinson: una nova perspectiva en la investigació amb cèl·lules mare i les seves aplicacions 

    Torrent Juan, Roger (Fecha de defensa: 2016-06-02)

    Parkinson’s disease (PD) is an incurable neurodegenerative disorder, mainly characterized by a progressive loss of midbrain dopaminergic (DA) neurons, located in the substantia nigra pars compacta (SNpc), and frequently ...