Facultat de Farmàcia i Ciències de l'Alimentació: Recent submissions
Now showing items 1-20 of 331
Innovación en la detección de Legionella y en el cultivo de bacterias exigentes
[spa] La legionelosis o enfermedad del legionario es una enfermedad infecciosa provocada por Legionella, una bacteria gramnegativa aeróbica estricta y un patógeno intracelular facultativo. Se transmite en humanos principalmente ...
Optimización del diagnóstico parasitológico de la leishmaniosis tegumentaria y caracterización de especie/s de Leishmania causantes del cuadro clínico en Cochabamba (Bolivia)
[spa] En Bolivia, la leishmaniosis tegumentaria (LT) abarca siete de los nueve departamentos, siendo uno de los países que presenta un mayor número de casos de leishmaniosis mucosa (LM) o leishmaniosis mucocutánea (LMC). ...
Study on Effects of Metformin and Transplantation of NPCs Separately and in Combination on Restores Cognitive Dysfunction and Histopathological Deficits in Mouse Model of Sporadic Alzheimer’s Disease
[eng] LOAD is a type of metabolic disorder known as type 3 diabetes. Metformin, a well-known anti-diabetic medication, has been introduced as a neuroprotective agent in recent years. On the hand, identifying the factors ...
Phenolic compounds and other constituents of extra virgin olive oil: Exploring the impact of cultivar, ripeness, malaxation, and high hydrostatic pressure
[eng] Olive oil represents a very important part of the economy of Spain and Catalonia. The value of this product, specifically extra virgin olive oil (EVOO), lies in its quality, both in terms of organoleptic and nutritional ...
The Contribution of the Polyamine Spermine to Plant Defense
[eng] Polyamines are essential in plant defense, with putrescine (Put), spermidine (Spd), and spermine (Spm) being the most abundant types. In response to various pathogens, including Pseudomonas syringae pv. tomato DC3000 ...
Prior knowledge and verification in macromolecular crystallography
[eng] Structural biology is essential for understanding the structure and dynamics of biological macromolecules, proteins, nucleic acids and their complexes, and to derive how the alterations produced in their structure ...
Characterization and prospective applications of melanin from black fungi in environmental biotechnology
[eng] Black fungi comprise a diverse group of ascomycetes characterized by their dark pigmentation due to the presence of melanin within their cells. This melanization process confers black fungi with a remarkable adaptability ...
Epigenomic and transcriptomic regulation of myeloid immunosuppression
[eng] This doctoral thesis delves into the complex mechanisms of the innate immune response, focusing on the role of myeloid cells such as monocytes and monocyte-derived dendritic cells in immunosuppression. These cells ...
Association between (poly)phenols and obesity: from the observational study to the clinical trial
[eng] (Poly)phenols from plants may help manage obesity due to their antioxidant and anti-inflammatory effects, but the exact types beneficial for obesity have yet to be clearly identified. High (poly)phenol diets may ...
Mecanismes i implicacions terapèutiques de la inhibició de l'epòxid hidrolasa soluble en la malaltia d’Alzheimer
[cat] La malaltia d'Alzheimer (MA) representa la causa més comuna de demència i és una de les malalties més prevalents en la societat, especialment a causa de l'augment de l'esperança de vida. Tanmateix, actualment, com a ...
Liposome Study of Baricitinib as a Novel Formula for Topical Treatment of Autoimmune Diseases
[eng] Autoimmune diseases are a diverse group of conditions where the immune system attacks the body's organs, affecting over 10% of the population, primarily women of working age. These diseases vary in severity and ...
Anàlisi “òmica” integrada de l’enteritis limfocítica secundària a enteropatia sensible al gluten. Descobriment de biomarcadors. Interès fisiopatològic i diagnòstic
[cat] La celiaquia es considera una malaltia d’elevada prevalença i la ingestió de gluten en pacients celiacs pot induir una gran varietat de simptomes incloent simptomatologia extraintestinal. Entre les estratègies de ...
Papel de la variabilidad viral, la expresión de RNA y la microbiota en el carcinoma asociado a la infección por el Virus del Papiloma Humano 16
[spa] El virus del papiloma humano (VPH) es el agente causal de múltiples cánceres ginecológicos, incluyendo el cáncer de vulva (VSCC). Si bien la infección por VPH es necesaria para el desarrollo de estas neoplasias, no ...
Evaluación de las asociaciones entre la ingesta de (poli)fenoles y el cambio de peso y el riesgo de mortalidad: Análisis en las cohortes EPIC-PANACEA y ESMaestras
[spa] INTRODUCCIÓN: La obesidad global es un desafío de salud pública, con más de 2.500 millones de adultos con sobrepeso y 890 millones con obesidad. En Europa, el 59% de la población adulta está afectada, especialmente ...
La no iniciació dels tractaments farmacològics en la població pediàtrica
[cat] L'adherència als tractaments farmacològics pediàtrics és un repte important per a la salut pública. Aquesta tesi doctoral investiga la no iniciació dels tractaments farmacològics en pacients pediàtrics a Catalunya, ...
The influence of fatty acids, phenolic compounds, and vitamin B12 on health in an older Mediterranean population
[eng] Chronic diseases are the leading cause of death in the world. Several of these conditions are related to the cardiovascular or cognitive system whose pathophysiology is closely linked to alterations in inflammatory ...
Seguiment farmacoterapèutic de malalts crònics complexos i integració en el marc de la gestió compartida de processos
[cat] La prevalença de pacients d’edat avançada amb malalties cròniques, polifarmàcia associada i alt risc de deteriorament funcional i cognitiu ha augmentat en els últims anys. Per això, l'atenció als pacients crònics ...
Study of the components and adherence to the Mediterranean diet on functional and cognitive ageing: from dietary assessment to a metabolomic approach
[eng] Healthy dietary patterns, such as the Mediterranean diet, have been linked to reduced chronic disease risk and mortality. However, the evidence regarding the impact of healthy dietary patterns on physical and cognitive ...
Development and applications of photoswitchable ligands for G protein-coupled receptors
[eng] G protein-coupled receptors (GPCRs) modulate diverse cellular responses to the majority of neurotransmitters and hormones within the human body. They exhibit much structural and functional diversity and are responsive ...
New strategies for improving the biotechnological production of taxanes
[eng] Plant specialized metabolism is the source of a wide range of bioactive compounds, some of which with relevant pharmacological properties. Nowadays, cancer is one of the main causes of mortality worldwide, therefore, ...
